Parkinson’s disease: symptoms, causes and treatment

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It is essential to understand Parkinson’s disease, detect it early, and find treatment. This blog explores the signs, risk factors, and management that patients with Parkinson’s disease, their families, and doctors can consider.  

Table of Contents 

  • What is Parkinson’s Disease 
  • Symptoms of Parkinson’s Disease 
  • Causes of Parkinson’s Disease 
  • Treatment of Parkinson’s Disease 
  • Conclusion 
  • Frequently asked questions 

What is Parkinson’s Disease? 

Parkinson’s disease is a chronic neurological condition that persists in the basal ganglia, which controls the movement of the voluntary muscles in the body. Parkinsonism is a long-standing disease of the central nervous system that causes changes in the patient’s movement and other dysfunctions. 

Symptoms of Parkinson’s Disease

It is essential to be able to identify these signs since this disorder is not usually diagnosed promptly, therefore making it difficult for Parkinson’s disease treatment.

Signs of Parkinson’s are usually not sudden and may present themselves in different ways in different people. They are broadly categorised into motor and non-motor symptoms. 

Motor Symptoms: 

Tremors: 

Tremor often begins in a limb, hand, or fingers and is marked by shaking or trembling. Akinetic rigidities or resting tremors are characteristic of Parkinson’s and occur when the affected limb is idle. 

Bradykinesia (Slowed Movement): 

That is, slowness in initiating and executing movements makes it difficult to perform activities that are considered routine. The disorder’s other symptoms include slow movement, difficulty walking straight, or reduced arm swinging. 

Muscle Rigidity: 

Restricted and painful movement in the limbs and the trunk. 

Postural Instability:

Usual gait disorders cause falls at later stages of the disease. Muscle cramps, increased joint pain, falls, and a decline in posture are some symptoms the patients suffer from. 

 Non-Motor Symptoms: 

Depression and Anxiety: 

Depression and Anxiety have become more prevalent in the older generation over the years and can be considered health-threatening conditions that severely impact the quality of life. 

Cognitive Impairment:

It is also worth mentioning that some patients may have mild cognitive impairment or could be diagnosed with dementia at some point. 

Sleep Disorders:

Difficulties that arise include insomnia or restless legs syndrome, REM sleep behaviour disorder, etc. 

Autonomic Dysfunction:

Some other problems that may arise include constipation, bladder problems, and changes in blood pressure owing to its background role by the autonomic nervous system. Due to such symptoms, they must be recognised early so that a doctor can be consulted and treatment can begin. 

Causes of Parkinson’s Disease

The exact cause of Parkinson’s disease is still not fully understood. Still, it is believed to result from genetic and environmental factors. The precise cause of Parkinson’s disease is still not fully understood, but it is believed to result from a combination of genetic and environmental factors:

Genetic Factors: 

Even though the majority of Parkinson’s disease cases are isolated, the disease also has some relation with genetic mutations. It is also more likely to occur in cases where a close family member has Parkinson’s Disease, though such occurrences are very rare. 

Environmental Factors:

Some toxins, like pesticides and herbicides, are known to cause Parkinson’s. Other factors include living in rural areas and drinking water from wells because of chemical exposure. 

Loss of Dopamine-Producing Cells: 

Parkinson’s disease is a disease characterized by progressive degeneration of the nerve cells in the substantia nigra, which is a part of the brain. It produces dopamine, the neurotransmitter responsible for the modulation of movements. This is due to decreased levels of dopamine, and this is also the cause of the abnormal brain activity and motor abnormalities that are characteristic of Parkinsonism. 

Lewy Bodies: 

Some protein deposits called Lewy bodies in the brain are present in Parkinson’s disease patients. Their presence is believed to indicate the condition, but this subpopulation’s specific role is not fully known. 

Knowledge of these factors enables the development of protective measures and drugs that can be used to treat specific cancer types. 

 Treatment for Parkinson’s Disease

While there is currently no cure for Parkinson’s disease, several treatment options are available to manage symptoms and improve the quality of life. 

Medications: 

Levodopa (L-DOPA): 

The drug that gives the best result when offered to Patients with Parkinson’s disease. In the brain, it is converted to dopamine, thus boosting the levels that may have been depleted. You cannot consume or take this medication until and unless prescribed by a certified doctor or a medical professional. 

MAO-B Inhibitors: 

These medications reduce the destruction of the brain’s dopamine by blocking the monoamine oxidase B enzyme. 

COMT Inhibitors:

Usually administered together with Levodopa to increase dopamine concentration’s duration by inhibiting an enzyme that degrades it. 

 Surgical Treatments: 

Deep Brain Stimulation (DBS): 

A process which involves implanting electrodes directly onto selected areas in the brain to control irregular impulses. However, early studies show that this pharmaceutical enhances motor symptoms in the advanced phase of Parkinson’s illness.

Therapies: 

Physiotherapy: 

Exercise is concerned with enhancing mobility, balance, and flexibility. It will also help patients understand the kind of exercises that are suitable for them, and a physiotherapist can teach this. 

Occupational Therapy: 

Assists the patients to continue their daily activities by recommending approaches that can be adopted. 

Speech Therapy: 

It helps with speaking and swallowing problems familiar to patients with Parkinson’s. 

Lifestyle and Support: 

Regular Exercise: 

Engaging in physical activity is important to keep the muscles flexing and to maintain balance. Walking, swimming, and other stretching exercises are all good options. 

Dietary Adjustments

A well-balanced diet of fibre, fluids, and nutrients keeps the body healthy and symptoms such as constipation in check. 

Support Groups and Counseling: 

Social and counselling support for the patients and their caregivers is vital for sustaining Parkinson’s. 

Therefore, preserving a timely and comprehensive approach using the help of a team of professionals can make a real difference in improving the quality of life for people with Parkinson’s disease. 

Conclusion 

Parkinson’s is a severe disorder that is hard to diagnose and is a significant problem in modern society due to the overwhelming number of people affected by it. Since there are ongoing studies to find new and more effective approaches and therapies, this may lead to improved methods of controlling the disease and its symptoms and, finally, to eradicating diabetes. However, this blog can help you understand Parkinson’s better than you did earlier. 

 Frequently Asked Questions 

1. Is there any way one can avoid Parkinson’s disease? 

At present, there is no method of preventing Parkinson’s disease; however, adopting a healthy lifestyle and avoiding toxic substances, as well as taking regular exercise, may also be beneficial. 

2. Is Parkinson’s disease fatal? 

While this disease is not deadly per se, it often leads to such complications as falls or pneumonia – which is fatal. 

3. Can young people be affected by Parkinson’s disease? 

Yes, Parkinson’s disease, though found predominately in the geriatrics, can still affect the young; this type is Young-Onset Parkinson’s Disease (YOPD).

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